Polyhexamethylene Guanidine (PHMG): Cov khoom no yog ib qho polymeric biguanide compound uas dhau ionization hauv cov kua dej. Nws cov hydrophilic moiety muaj lub zog zoo, ua kom nws nqus tau ntau yam kab mob thiab cov kab mob - uas feem ntau muaj cov nqi tsis zoo - thiab tom qab nkag mus rau lawv cov cell membranes. Los ntawm inhibiting cov synthesis ntawm liposomes nyob rau hauv daim nyias nyias, nws induces kab mob apoptosis, yog li ua tau zoo bactericidal kev ua tau zoo.
Raws li cationic polymer, cov khoom no exerts nws antimicrobial nyhuv feem ntau los ntawm dissolving lipids thiab hloov cov permeability ntawm cov kab mob cell membranes, yog li cuam tshuam intracellular metabolic dab. Nws muaj cov tshuaj tua kab mob dav dav, ua kom pom kev ua tau zoo tiv thaiv Gram- cov kab mob zoo, Gram- cov kab mob tsis zoo, thiab pwm. Tsis tas li ntawd, nws yog tus cwj pwm los ntawm kev tsis muaj xim, tsis muaj ntxhiab, tsis yog - ua rau tawv nqaij, tsis yog - tshuaj lom, thiab tsis yog - corrosive.
Chlorhexidine Gluconate: Cov khoom no muaj xim tsis muaj xim lossis daj daj, ze li pob tshab, thiab kua nplaum me ntsis; nws tsis muaj ntxhiab los yog muaj ntxhiab tsw tsw heev. Nws yog miscible nrog dej thiab soluble hauv ethanol lossis acetone. Relative Density: 1.060-1.070 g / mL (ntawm 25 degree). Lwm cov npe Suav suav nrog: 1,6-bis(N1-p-chlorophenyl-N5-biguanido) hexane digluconate; Chlorhexidine Gluconate; Chlorhexidine Digluconate; thiab Chlorhexidine (20% w / v aqueous tov). Nws thawj daim ntawv thov yog ua tshuaj tua kab mob thiab tshuaj tua kab mob; Nws nthuav tawm lub zog, dav-spectrum bacteriostatic thiab bactericidal kev ua haujlwm, zoo tiv thaiv kab mob Gram-positive thiab Gram-negative. Nws yog qhia rau kev siv sab nraud hauv kev tua kab mob ntawm tes thiab tawv nqaij, nrog rau qhov txhab dej.
